The terms sociopath and psychopath do not appear in the Bible. However, the Bible does mention behaviors that are characteristic of those that today are described by the nearly synonymous terms sociopathic and psychopathic.
In today’s criminal and psychological literature, a sociopath or psychopath is identified as one who is characterized by extreme self-centeredness and immaturity, shallow emotions (including reduced fear, a lack of empathy and remorse, low tolerance for stress, and little response to positive motivations), cold-heartedness, superficial charm, irresponsibility, impulsivity, criminality, a parasitic lifestyle and a desire to manipulate others. A psychopath is one who compulsively performs criminally selfish acts with no apparent conscience or concern about the welfare of his victims.
The Bible identifies such sociopathic and psychopathic behavior as among the severest moral and spiritual effects of man’s fall into sin. Jesus described such sins as arising from evil hearts (Mark 7:20–23). The apostle Paul identified godlessness as the root of such a deadly heart (Romans 1:28–32). The sociopathic heart produces the worst characteristics of sinful man’s nature (Romans 8:5–8), the worst effects of both genetic and environmental moral degradation. Early in human history, God wiped out all but eight people because of such universally incorrigible behavior (Genesis 6:5–13). Deuteronomy 21:18–21 prescribes for the Old Testament nation of Israel the legal consequence of such behavior: execution by stoning. Apparently, such behavior was considered by God to be so disruptive and damaging to the family and to society, so contrary to the character of the people that bore His name and supposedly reflected His image, as to be intolerable.
The New Testament does not offer specifics on civic dealing with these serious problems. Its teachings about morality and immorality of every kind, and its hopeful appeals and invitations to repentance, conversion, and transformed life in Christ, certainly apply to a psychopath as to any sinner. Paul, describing conduct that included sociopathic characteristics, wrote to one congregation of believers in Jesus Christ, “Such were some of you” (1 Corinthians 6:9–11, emphasis added). God is able to rescue and restore to righteousness the most corrupt heart. See Ephesians 4:24; Colossians 3:1–17; Romans 7; Romans 8:1–17 and 28–30.
 Got Questions Ministries. (2010). Got Questions? Bible Questions Answered. Bellingham, WA: Logos Bible Software.